Core Research Team


Yufen GUO, MSc   Project Manager - Focus on EFADchip® Development

Ms. Yufen Guo is a molecular biologist. She received holds a Master’s degree in molecular plant pathology from China Agricultural University and a Bachelor’s degree in agriculture from Sichuan Agricultural University. She joined HKLife as a Project Manager in 2011 and is currently responsible for the process development of HKLife’s diagnostic platform.

1) Chen X, Chen H, Yuan JS, Köllner TG, Chen Y, Guo Y, et al. The rice terpene synthase gene OsTPS19 functions as an (S)-limonene synthase in planta, and its overexpression leads to enhanced resistance to the blast fungus Magnaporthe oryzae. Plant Biotechnology Journal. 2018;16(10):1778-87.


Bai-Liang HE, PhD   Research Scientist - Focus on EFADchip® & BioRadar Process Validation

Dr. Alex Bai-Liang HE is a biomedical scientist. He received his PhD degree from The University of Hong Kong specializing in hematology in 2016. He was awarded the “Li Ka Shing Prize” for his best PhD thesis within the Faculties of Dentistry, Engineering, and Medicine. During his PhD study, his research focused on the identification of novel diagnostic biomarkers and therapeutic targets for human blood cancers, and the original works were published in several reputed journals, including Blood, Science Translational Medicine, Nature Communications, Elife, Blood Reviews among others. He has joined HKLife as a Research Scientist and participates in the development of EFADchip® & BioRadar platform and other biomedicine-related products.

1) He BL, Shi X, Man CH, Ma AC, Ekker SC, Chow HC, et al. Functions of flt3 in zebrafish hematopoiesis and its relevance to human acute myeloid leukemia. Blood. 2014;123(16):2518-29.
2) Lam SS, He BL, Leung AY. Treatment of acute myeloid leukemia in the next decade - Towards real-time functional testing and personalized medicine. Blood Reviews. 2017;31(6):418-25.
3) Shi X, He BL, Ma AC, Leung AY. Fishing the targets of myeloid malignancies in the era of next generation sequencing. Blood Reviews. 2016;30(2):119-30.



Iris HO, BSc   Chip Production Leader - Focus on Chip Production

Ms. Iris Ho is a chemical engineer and received her Bachelor’s degree from Guangdong University of Technology. Before joining HKLife in 2015, she worked at several globally renowned manufacturing enterprises, such as Philips, NXP Semiconductors and Johnson Electric which equipped her with proficient technical and management skills in the production line. Currently, as a Production Leader, she is responsible for the preparation and production of EFADchip®.



Timothy HO, PhD   Research Scientist - Focus on EFADchip® Diagnosis Optimization and Molecular Test Kit Development

Dr. Timothy Ho is a biochemist. He graduated from the Hong Kong University of Science and Technology with a Master’s and a PhD degree in biochemistry, biopsychiatry and phytochemistry. Dr. Ho holds two pending patents which he obtained during his PhD training. After his PhD, he continued as a postdoctoral researcher. At HKLife, he is responsible for process validation and stability testing of HKLife’s diagnostic platform.

1) Yeung RK, Xiang ZH, Tsang SY, Li R, Ho TYC, Li Q, Hui CK, Sham PC, Qiao MQ, Xue H. Gabrb2-knockout mice displayed schizophrenia-like and comorbid phenotypes with interneuron-astrocyte-microglia dysregulation. Translational Psychiatry. 2018; 8(1): 128.
2) Ho TYC, Xue H. Effects of 4 Flavonoids from Scutellaria Baicalensis on Different Cancer Cell Lines. World Science and Technology/Modernization of Traditional Chinese Medicine and Materia Medica. 2016;18(11):1845-1854.
3) Ho TYC, Xue H, 2016. Dispersed Mobile-Phase Countercurrent Chromatography. Separations. 2016;3(4):32.



Zhiyan HU, MSc  Engineer  - Focus on BioRadar Engineering Design and Validation

Ms. Zhiyan HU is a mechanical engineer. She received a Master’s degree in mechanical design & theory from China University of Mining and Technology (Beijing) and a Bachelor’s degree in construction machinery from North China Institute of Water Resources and Hydropower. Before joining HKLife, Ms. Hu worked at Beijing Jingyi Century Electronic Co., LTD and Beijing Yiwang Intelligent Manufacturing Research Institute Co., LTD. As a Mechanical Engineer, she has extensive experience in structural design, pneumatic system, fluid control system, non-standard equipment, and automation process realization. At HKLife, she is responsible for the design and verification of BioRadar.

1) Hu Z. Determination of Percussion Drill Stroke. Western Prospecting Project. 2004(12):129-30.



Disha KOHLI, MMedSc  R&D Associate – Focus on the development of EFADchip® Platform

Ms. Disha Kohli completed her Bachelor’s degree in biomedical sciences from the University of Nottingham in 2017 and further went on to pursue a Master’s degree in medical sciences while specializing in medical microbiology from the University of Hong Kong in 2018. She possesses substantial medical writing and laboratory experience. Currently, as a R&D Associate at HKLife, she is responsible for aiding in the development process of EFADchip® and providing assistance in technical writing as well as IP applications.


Disha Kohli


Wanying LI, PhD  Post-Doctoral Researcher  - Focus on Liquid Biopsy Molecular Diagnostics for Cancer

Dr. Wanying Li is a biologist and graduated from China Agricultural University with a PhD degree in biochemistry and molecular biology. She has published one research paper and owns one patent on maize silk-specific ZmbZIP25 promoter. At HKLife, she works as a Post-Doctoral Researcher and leads the development of molecular diagnostics for cancer using HKLife’s diagnostic platform.

Li W, Yu D, Yu J, Zhu D, Zhao Q. Functional Analysis of Maize Silk-Specific ZmbZIP25 Promoter. International Journal of Molecular Sciences. 2018;19(3):822.



Wei LIU, MSc   Assistant R&D Manager - Focus on Research Management 

Ms. Wei Liu received a Master’s degree in phytomolecular pathology from Chinese Academy of Agricultural Sciences and a Bachelor’s degree in plant protection science from Shanxi Agricultural University. She has plenty of experience in project management and scientific writing. She joined HKLife in 2014 and is currently appointed as an Assistant R&D Manager to assist CSO in project management and file documentation.

Zheng N, Zhai W, Liu W, Zhang S, Zhang W, Han R, et al. Cotton factors influencing maturation and senescence and control strategies. Plant Physiology Journal. 2014;50(9):1310-4.



Xiangxin SUN, MSc   Project Manager - Focus on Sample Preparation Methodology

Mr. Xiangxin Sun received his Master’s degree in molecular biology and virology from the Academy of Military Medical Sciences of China and a Bachelor’s degree in biological sciences from Shanxi Agricultural University. Before joining HKLife, Mr. Sun worked for several IVD companies and has applied for more than 20 patents. He is familiar with quality management system, ISO 13485 and NMPA medical device registration procedures. He joined HKLife in 2018 as a Project Manager and is leading the process development of automatic clinical sample preparation for HKLife’s diagnostic platform.

Sun X, Liu Y, Yang Y, Zhang S, Hu R. Preparation and Immunity Effect Assessment of an Inactivated Vaccine against Canine Parvovirus. China Animal Husbandry & Veterinary Medicine 2011;38(9):175-7.

A sample point template used in assisted DNA electrophoresis. (CN 204964442 U)
2) Biomolecular extraction device. (CN 206477001 U)
3) Biological sample extractor. (CN 206562437 U)
4) A device for extracting biomolecules from magnetic beads. (CN 206232739 U) 



Shuangyan WANG, MSc   Project Manager - Focus on NASBA Technology

Ms. Shuangyan Wang received a Master’s degree in molecular biology from the Institute of Oceanology, Chinese Academy of Sciences in 2012 and a Bachelor’s degree in life sciences from Liaocheng University. She joined HKLife in 2012 and has been involved in many R&D projects, including the development of enzymes, qPCR testing kits and sample pretreatment process. As a Project Manager, she is leading the development of NASBA technology for HKLife’s diagnostic platform.

Wang S, Cui Z, Liu Y, Li Q, Song C. Identification and characterization of a serine protease inhibitor (PtSerpin) in the swimming crab Portunus trituberculatus. Fish and Shellfish Immunology. 2012;32(4):544-50.
2) Wang S, Cui Z, Liu Y, Li Q, Song C. The first homolog of pacifastin-related precursor in the swimming crab (Portunus trituberculatus): characterization and potential role in immune response to bacteria and fungi. Fish and Shellfish Immunology. 2012;32(2):331-8.
Wang S, Cui Z, Liu Y, Li Q, Song C. The first kazal-type serine proteinase inhibitor in the swimming crab Portunus trituberculatus involved in immune response to bacteria and fungi. Aquaculture. 2012;356-357:55-60.



Bin YANG, PhD   Project Manager - Focus on Probe Development

Dr. Bin Yang is a biologist and received a PhD degree in biochemistry and molecular biology from China Agricultural University. She has substantial research experience in the biosafety evaluation of genetically modified cloned animals. After joining HKLife in 2009, she has serves as a Researcher, Technical Support and a Sales Manager. Currently, as a Project Manager, she oversees the probe development of HKLife’s platform.

1) Yang B, Wang J, Tang B, Liu Y, Guo C, Yang P, et al. Characterization of bioactive recombinant human lysozyme expressed in milk of cloned transgenic cattle. PloS One. 2011;6(3):e17593.
2) Yin HF, Fan BL, Yang B, Liu YF, Luo J, Tian XH, et al. Cloning of pig parotid secretory protein gene upstream promoter and the establishment of a transgenic mouse model expressing bacterial phytase for agricultural phosphorus pollution control. Journal of Animal Science. 2006;84(3):513-9.



Huajian ZHAO, PhD   Post-Doctoral Researcher - Focus on Anti-Microbial Resistance

Dr. Huajian Zhao is a biologist and received his PhD degree in biochemistry and molecular biology from Nanjing Agricultural University He completed his post-doctoral training at South Dakota State University. Dr. Zhao has extensive research experience in microbial detection, genome sequencing and bioinformatics analysis. Also, he has been invited as a reviewer to Archives of Virology several times. At HKLife, he works as a Post-Doctoral Researcher and leads anti-microbial resistance gene probe development for HKLife’s diagnostic platform.

Zhao H, Han Q, Zhang L, Zhang Z, Wu Y, Shen H, et al. Emergence of mosaic recombinant strains potentially associated with vaccine JXA1-R and predominant circulating strains of porcine reproductive and respiratory syndrome virus in different provinces of China. Virology Journal. 2017;14(1):67.
Zhao H, Hui R, Leung F. PCV-2 and PRRSV is Common in Henan, China from November 2013 to October 2014. 2014 North American PRRS Symposium; Chicago, Illinois. 2014.
Zhao H, Jiang J, Singh Brar M, Leung F. A fast and cost-effective method for Whole Genome Sequencing (WGS) of PRRSV type 2 directly from field samples in China. 2015 North American PRRS Symposium; Chicago, Illinois. 2015.


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